Science explained
SPG4 in children: what parents need to know
SPG4 can begin in childhood. What is known about onset, diagnosis, care today, inheritance and research, explained for parents, with medical sources.
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News
What is happening in SPG4 research, explained clearly and with sources for parents and families, plus updates on the campaign and the association.
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Science explained
What is SPG4? A guide for families
What an SPG4 diagnosis means, how it shows itself, how it is inherited, how it is confirmed and what can be done for symptoms today. In plain language, with medical sources.
Science explained
SPG4 and SPG50: why they are different diseases
The Melpida gene therapy for SPG50 has given many families hope. We explain what it showed, why SPG4 is a different disease and what can realistically be learnt from it.
Research
Where SPG4 research stands in November 2026
An overview of the strategies being studied in the laboratory, the clinical studies that are registered (and those still missing) and the limits of the evidence so far.
Transparency
How we verify every amount
What "money raised" means on this site: verified amounts only, pledges shown separately, conversion at the BNR rate, protection against double counting and a log of every change.
Research news, once a month
Clear summaries of studies relevant to SPG4, campaign progress and financial reports. No spam; unsubscribe at any time.